A suit-wearing, briefcase-carrying baby pairs up with his 7-year old brother to stop the dastardly plot of the CEO of Puppy Co.

6 months after the incidents involving the lethal videotape, new clues prove that there is a new evil lurking in the darkness.

The Cortez siblings set out for a mysterious island, where they encounter a genetic scientist and a set of rival spy kids.

A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.