Blade, now a wanted man by the FBI, must join forces with the Nightstalkers to face his most challenging enemy yet: Dracula.

Blade forms an uneasy alliance with the vampire council in order to combat the Reapers, who are feeding on vampires.

A half-vampire, half-mortal man becomes a protector of the mortal race, while slaying evil vampires.

A federal agent uncovers lucrative toxic waste dumps in Appalachia and must deal with the locals who want to keep their ‘gold mine’ secret.