When three different animals become infected with a dangerous pathogen, a primatologist and a geneticist team up to stop them from destroying Chicago.

In the aftermath of a massive earthquake in California, a rescue-chopper pilot makes a dangerous journey with his ex-wife across the state in order to rescue his daughter.

Sean Anderson partners with his mom’s husband on a mission to find his grandfather, who is thought to be missing on a mythical island.

The on-going war between the canine and feline species is put on hold when they join forces to thwart a rogue cat spy with her own sinister plans for conquest.